Depression model 02

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Depression is a disease with high morbidity, disability and recurrence rates, with the main clinical manifestations of loss of pleasure, diminished will, slow thinking, indifference to the outside world, and in severe cases, disabling and suicidal behavior. Drug-induced depression animal models can both predict antidepressant efficacy and explore the underlying mechanisms of depression, and because of its simplicity and ease of use, it is mostly used for the initial screening of antidepressants.

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