Osteoporosis model 01

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Osteoporosis (OP) has become one of the chronic diseases that seriously threaten human health, and with the aging of our population, osteoporosis will become a social problem. Selecting and establishing an appropriate osteoporosis animal model is a prerequisite for osteoporosis research. There are many methods of osteoporosis modeling, such as ovariectomy, retinoic acid method, glucocorticoid method, etc. Although ovariectomized rats are the “gold standard” for postmenopausal osteoporosis research, they also have drawbacks (no Harvard's reconstruction, can't be used to study the changes of cortical bone).

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